Redneck Mafia
UKC Moderator
Registered: Aug 2013
Location: Seneca, Mo
Posts: 5902 |
quote: Originally posted by Richard Lambert
"Seems to have helped" a "bunch of folks"??? Oh my goodness, well that is certainly clear. If you understand how it works, would you please explain it?
The causative agent of the current COVID-19 pandemic, SARS-CoV-2, is a single stranded positive sense RNA virus that is closely related to severe acute respiratory syndrome coronavirus (SARS-CoV). Studies on SARS-CoV proteins have revealed a potential role for IMPα/β1 during infection in signal-dependent nucleocytoplasmic shutting of the SARS-CoV Nucleocapsid protein (Rowland et al., 2005;_Timani et al., 2005;_Wulan et al., 2015), that may impact host cell division (Hiscox et al., 2001;_Wurm et al., 2001). In addition, the SARS-CoV accessory protein ORF6 has been shown to antagonize the antiviral activity of the STAT1 transcription factor by sequestering IMPα/β1 on the rough ER/Golgi membrane (Frieman et al., 2007). Taken together, these reports suggested that ivermectin's nuclear transport inhibitory activity may be effective against SARS-CoV-2.
In vitro studies showed a viral load reduction of -5000 after 48hrs.
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Cheyenne & Jennifer Cummings
Seneca , MO
(417)317-4815
"TEAM MAFIA"
*NATIONAL GRNITECH GRCH GRNITECH(5) HALL OF FAME PKC PLATIUM CH REDNECK BACKWOODS SHACK
2014 OK STATE CH, 2015 MO PKC LEADER, 2016 PKC NATIONALS SEMIFINALIST, 2016 UKC TOP 20, 2O17 UKC WORLD CHAMPIONSHIP 3RD PLACE, 2018 PKC SENIOR SHOWDOWN TRUCK HUNT FINAL 4, 2018 MO PKC STATE CHAMPION, 2019 AUTUMN OAKS NATIONAL GRNITE CH, 2019 PKC WORLD CH SEMIFINALIST. 2021 PKC SENIOR SHOWDOWN TRUCK HUNT FINAL 4.
*PKC WORLD CHAMPION PLATNIUM CHAMPION GRNITECH SHACK'S HEATHER ISLAND SOUTHERN STOGIE
2021 OKLAHOMA STATE CHAMPION, 2022 PKC WORLD CHAMPION, 2022 MO PKC STATE LEADER PRO SPORT TRUCK WINNER
RIP
*GRNITECH PKC SCH REDNECK MAFIA PKC HALL OF FAME REPRODUCER INDUCTED 2022
*GRNITECH CH PKC SILVER CH REDNECK SHACK ATTACK aka TAC 2018 OKLAHOMA STATE CHAMPION, 2020 MO PKC STATE LEADER
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